Sloan Pharma Sarl Bertrange Cham Branch Alte Steinhauserstr. 21 6330 Cham Switzerland info@sloanpharma.com Date: Dear Sir/Madam I was shocked to learn that your company is carrying out cruel animal experiments on 46,800 mice for the batch testing of your botulinum toxin B product Neurobloc. In this so-called LD50 test, groups of mice are injected with different doses of the substance in the abdomen. The mice are subjected to terrible pain and after up to three or four days of suffering they die of suffocation. Already in 2011, the first cell-based assay was approved, developed by the company Allergan for the batch testing of botulinum toxin A products. In the meantime, two other manufacturers have received approval for their cell tests. I am aware that botulinum toxin B is different from A. However, other manufacturers have proven that the replacement of the cruel animal test is possible. I urge you to develop a non-animal testing method. For the period of time until the approval of this non-animal assay the production of Neurobloc must be suspended. I will boycott all your products and encourage all my friends to do the same as long as you are responsible for LD50 tests. I’m looking forward to hearing from you. Yours sincerely